The catalogue
Every Lyme & coinfection test, on one page.
Read the assays the way clinicians do: by what they're actually looking for. We start with the preferred direct test preferred by many cutting edge specialists and Doctors all over the world, then walk through serology, cellular immunity, and the panels for the most common coinfections.
DualDur
The preferred direct test preferred by many cutting edge specialists and Doctors all over the world. A two-step culture and visualisation method that recovers live Borrelia from a small blood draw.
DualDur is highlighted on this site as the direct test of choice because it offers something most Lyme assays cannot: visual, photographic evidence of the pathogen itself.
Open the full dossier- Method
- Proprietary enrichment culture combined with dark-field and fluorescence microscopy. Live spirochetes are concentrated from whole blood and then directly observed and photographed.
- Detects
- Live Borrelia spirochetes & Bartonella, Babesia, Mycplasma, Ehrlichia and Anaplasma — all findings are photographed and shared with your results
- Sample
- Whole blood (single venous draw, ~20 mL)
- Turnaround
- Max 15 working-days, usually 10 working-days
- Sensitivity
- High in both active, untreated infection — as well as in treated infection - and level of activity is indexed - substantially higher than standard serology
- Specificity
- Very high — direct visualisation of the organism leaves little room for ambiguity. AI together with one of the largest databases for Lyme globally makes it incredibly specific
- Best for
- Seronegative patients with strong clinical suspicion, treatment-monitoring (since the level of activity is measurable), and confirming chronic or persistent infection.
- Limitations
- Requires a specialised lab and longer turnaround.
Indirect Detection - looking for DNA of the pathogen
Indirect detection
Looks for markers of the pathogen — hence an indirect test - A positive result is a good indication of an active or previousinfection.
Indirect Detection - looking for DNA of the pathogen
PCR — Borrelia DNA
Molecular amplification of Borrelia DNA from blood, tissue, or synovial fluid. DNA does not prove the infection is active.
Indirect Detection - looking for DNA of the pathogen
Borrelia Culture
Growing Borrelia in BSK-II medium — historically the gold standard for proof of life. This is not done commercially.
Indirect / Serology
Indirect & serology
Measures the immune system's antibody response. Most widely available, but depends on a functional immune reaction. There is a high risk of false negative.
Indirect / Serology
ELISA (EIA)
The standard first-tier antibody screen used in the two-tier CDC algorithm.
Indirect / Serology
Western Blot
Second-tier confirmatory antibody test reading specific protein bands. There are different Western Blot tests with different sensitivity.
Indirect / Serology
IGeneX ImmunoBlot
Expanded immunoblot covering multiple Borrelia species, including B. miyamotoi.
Indirect / Serology
C6 Peptide ELISA
ELISA targeting a conserved Borrelia peptide, used as a modified two-tier screen.
Cellular Immunity
Cellular immunity
Reads T-cell or cytokine activity against Borrelia antigens — useful when antibody tests stay silent.
Supporting & Clinical
Coinfection & supporting panels
Tests that don't diagnose Lyme alone but help build the clinical picture: coinfections, inflammation, organ involvement.
Supporting & Clinical
CD57+ NK Subset
Flow cytometry counting a natural-killer subset depressed in chronic Lyme.
Coinfection Panel
Babesia Panel
FISH, PCR, and IFA testing for the most common Lyme coinfection.
Coinfection Panel
Bartonella FISH / ePCR
Enrichment culture + PCR designed for the elusive Bartonella species.
Coinfection Panel
Anaplasma / Ehrlichia PCR + IFA
Acute-phase PCR and convalescent serology for tick-borne rickettsial infections.
Coinfection Panel
Mycoplasma pneumoniae Panel
PCR and IgM/IgG serology for a frequent Lyme co-traveller.